官网链接
折扣/货期| 货号：SYN-1213-M001 | 规格：1 mg | 目录价：￥756 |
| 货号：SYN-1213-M005 | 规格：5 mg | 目录价：￥1204 |
| 货号：SYN-1213-M010 | 规格：10 mg | 目录价：￥1820 |
| 货号：SYN-1213-M050 | 规格：50 mg | 目录价：￥5292 |
| 货号：SYN-1213-M100 | 规格：100 mg | 目录价：￥询价 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
LEE011
别名:
LEE-011; Ribociclib
产品描述:
Orally available cyclin-dependent kinase (CDK) inhibitor targeting cyclin D1/CDK4 and cyclin D3/CDK6 cell cycle pathways, with potential antineoplastic activity. Specifically inhibits CDK4 and 6, thereby inhibiting retinoblastoma (Rb) protein phosphorylation. Inhibition of Rb phosphorylation prevents CDK-mediated G1-S phase transition, thereby arresting the cell cycle in the G1 phase, suppressing DNA synthesis and inhibiting cancer cell growth. Overexpression of CDK4/6, as seen in certain types of cancer, causes cell cycle deregulation.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
434.5
产品形式:
solid
产地:
瑞士
纯度:
>95%
CAS号:
1211441-98-3
分子式:
C23H30N8O
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