官网链接
折扣/货期| 货号：SYN-1213-M001 | 规格：1 mg | 目录价：￥756 |
| 货号：SYN-1213-M005 | 规格：5 mg | 目录价：￥1204 |
| 货号：SYN-1213-M010 | 规格：10 mg | 目录价：￥1820 |
| 货号：SYN-1213-M050 | 规格：50 mg | 目录价：￥5292 |
| 货号：SYN-1213-M100 | 规格：100 mg | 目录价：￥询价 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
LEE011
别名:
LEE-011; Ribociclib
产品描述:
Orally available cyclin-dependent kinase (CDK) inhibitor targeting cyclin D1/CDK4 and cyclin D3/CDK6 cell cycle pathways, with potential antineoplastic activity. Specifically inhibits CDK4 and 6, thereby inhibiting retinoblastoma (Rb) protein phosphorylation. Inhibition of Rb phosphorylation prevents CDK-mediated G1-S phase transition, thereby arresting the cell cycle in the G1 phase, suppressing DNA synthesis and inhibiting cancer cell growth. Overexpression of CDK4/6, as seen in certain types of cancer, causes cell cycle deregulation.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
434.5
产品形式:
solid
产地:
瑞士
纯度:
>95%
CAS号:
1211441-98-3
分子式:
C23H30N8O
您可能感兴趣的产品
2-Oxoarginine
货号：9004337-1 mg
LCC-12 (formate)
货号：46743-1 mg
Guanosine 5′-diphospho-D-mannose (sodium salt)
货号：46575-10 mg
Necrocide 1
货号：46570-1 mg
2'-O-Methylpseudouridine
货号：46554-1 mg
Nampt Activator-1
货号：46510-10 mg
1-(3-Hydroxyphenyl)dihydropyrimidine-2,4(1H,3H)-dione
货号：46507-100 mg
DS-6930
货号：46506-1 mg
促销活动
精品推荐
复制QQ号成功，请打开QQ后添加好友进行咨询