| 货号:SYN-1214-M001 | 规格:1 mg | 目录价:¥910 |
| 货号:SYN-1214-M005 | 规格:5 mg | 目录价:¥1204 |
| 货号:SYN-1214-M010 | 规格:10 mg | 目录价:¥1512 |
| 货号:SYN-1214-M050 | 规格:50 mg | 目录价:¥5292 |
| 货号:SYN-1214-M100 | 规格:100 mg | 目录价:¥询价 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
AZD1208
别名:
AZD-1208
产品描述:
Potent, highly selective and orally available Pim kinase inhibitor that effectively inhibits all three isoforms Pim-1, Pim-2 and Pim-3 at < 5nM or < 150 nM in enzyme and cell assays, respectively. Potently inhibits colony growth and Pim signalling substrates in primary AML cells from bone marrow that are Flt3 wild-type or Flt3 internal tandem duplication mutants. Upregulation of Pim kinases is observed in several types of leukemias and lymphomas. Pim-1, -2 and -3 promote cell proliferation and survival downstream of cytokine and growth factor signaling pathways.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
379.5
产品形式:
solid
产地:
瑞士
纯度:
>95%
CAS号:
1204144-28-4
分子式:
C21H21N3O2S
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