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折扣/货期| 货号：IAX-700-100-L001 | 规格：1 ml | 目录价：￥3192 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Lipodisq Control Sterile Solution
别名:
Detergent-free Nano-formulation made of Styrene-maleic Acid Lipid Particles (SMALP)
产品描述:
A nanoparticle (11-40nm) drug delivery system comprising a discoidal phospholipid bilayer membrane stabilized by a chaperone molecule annulus. Internal properties of the phospholipid membrane support the disposition and stabilization of drug molecule candidates and preserve the native conformation of membrane molecules. The resulting encapsulated actives are rendered water-soluble and specialized for intra-cellular penetration/delivery via endosomal uptake mechanisms. Lipodisq™ solutions show a good safety profile and are suitable for in vitro and in vivo investigations.
保存温度:
+4°C
运输温度:
Ambient
产品形式:
liquid
存储溶液:
Liquid, detergent-free discoidal nano-formulation made of styrene-maleic acid lipid particles (SMALP), lecithin and sterile water.
产地:
瑞士
生物活性:
Cell culture tested (human macrophage cell line) (MTT).
Recommended starting dilution: 1:200 or higher.
Optimal working concentrations depend on the applications and need to be determined.
Published procedures using Lipodisq formulations (Curcumin and IAXO TLR4 antagonists) in vivo rodent models at 3-10mg/kg.
Recommended route of administration is subcutaneous (s.c.) with oral or nasal application as a possible alternative, which needs to be optimised.
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