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折扣/货期| 货号：SIH-395-5G | 规格：5 g | 目录价：￥648 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Metformin Hydrochloride
别名:
N,N-Dimethylimidodicarbonimidic diamide hydrochloride
产品描述:
Autophagy inducer
保存温度:
-20ºC
运输温度:
Shipped Ambient
预期分子量:
165.6
产品形式:
White crystalline powder.
产地:
加拿大
功能与背景:
Metformin Hydrochloride is an antidiabetic agent which reduces blood-glucose levels as well as improves insulin sensitivity. Metformin has also been shown to inhibit hepatic gluconeogenesis via activation of LKB1-AMPK (AMP-activated protein kinase) pathway. The activation of this pathway has also been seen to have an antiproliferative and pro-apoptotic effect in cancer cells. Lastly, Metformin is believed to induce autophagy through inhibition of the mTORC1 pathway. Neuroprotective and lowers alpha synuclein phosphorylation.
纯度:
≥97%
来源:
Synthetic
CAS号:
1115-70-4
分子式:
C4H11N5•HCl
溶解度:
Soluble to 100 mM in water and to 50 mM in DMSO.
PubChem CID:
14219
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