| 货号:CDX-M0558-M010 | 规格:10 mg | 目录价:¥462 |
| 货号:CDX-M0558-M025 | 规格:25 mg | 目录价:¥1022 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Mildronate dihydrate
别名:
Meldonium; MET 88; Quaterin; THP
产品描述:
Mildronate is a structural analog of gamma-butyrobetaine (gammaBB), an intermediate in the biosynthesis of carnitine and a modulator of energy metabolism. It blocks carnitine synthesis by inhibiting gammaBB hydroxylase (BBOX) and, less potently, carnitine acetyltransferase (CrAT). Through these actions, mildronate reduces the levels of free carnitine and long chain acyl carnitine. This leads to suppressed fatty acid metabolism and mitochondrial uncoupling during oxidative conditions, resulting in cardioprotective, antidiabetic and neuroprotective effects. Mildronate also improves cognition and reduces amyloid-beta pathology in a mouse model of Alzheimer’s disease.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
182.22
产品形式:
solid
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
86426-17-7
分子式:
C6H14N2O2 . 2H2O
促销活动
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