货号:AG-CN2-0489-G001 | 规格:1 g | 目录价:¥180 |
货号:AG-CN2-0489-G005 | 规格:5 g | 目录价:¥540 |
货号:AG-CN2-0489-M250 | 规格:250 mg | 目录价:¥120 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
N-Acetyl-D-glucosamine
别名:
D-GlcNAc; GlcNAc; NAG; 2-(Acetylamino)-2-deoxy-D-glucose
产品描述:
N-Acetyl-D-glucosamine (D-GlcNAc) is a non-toxic derivatized glucose monosaccharide found in polymers (Peptidoglycan; PGN) of bacterial cell walls, chitin (e.g. fungi, invertebrates, crustaceans), hyaluronic acids and various glycans. It is also synthesized in the glycosylation pathway as uridine diphosphate (UDP-GlcNAc), which can then be released following degradation of glycosylated proteins. Atypical microbial danger signal that acts as a new activator of NLRP3 inflammasome by dissociating the enzyme hexokinase from the mitochondria. D-GlcNAc inhibits purified hexokinase, which is also involved in the glucose metabolism and obesity in mM range. For hexokinase dissociation from the mitochondria much higher concentrations are needed. Acceptor substrate for galactosyltransferases. Inhibits the lectin WGA and is used to identify, differentiate and characterize N-acetyl-beta-D-hexosaminidase(s). Used in the treatment of osteoarthritis and inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease. Significantly enhances the prevention of joint damage and inhibits elastase activity and superoxide release from human polymorphonuclear leukocytes. Acts as a cytoprotective agent restoring the integrity and normal function of mucous membrane in humans. D-GlcNAc enhances the proliferation and collagen expression of fibroblasts, reduces hyperpigmentation and is therefore considered a valuable ingredient in cosmetics for improving skin wrinkles and color. Important substrate for the production of sialic acids. Used in multiple other applications in drug development and food supplement, based on a newly described bio-wave model.
宿主来源:
Prepared by using chitin as a substrate.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
221.2
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>95% (NMR)
CAS号:
7512-17-6
分子式:
C8H15NO6
溶解度:
Soluble in DMSO (10mg/ml) or water.
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