深圳欣博盛生物科技有限公司 a1

NAI-108
货号:AG-CN2-0308-C500 规格:500 ug 目录价:¥3120
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
NAI-108
别名:
Lantibiotic NAI 108 A1/A2 Mixture
产品描述:
Antibacterial class I lantibiotic. Brominated variant of NAI-107 (AG-CN2-0307 https://adipogen.com/ag-cn2-0307-nai-107-microbisporicin.html ). Inhibits cell wall synthesis and consequently bacterial growth by forming a complex with lipid intermediate II (Lipid II), a key intermediate in peptidoglycan biosynthesis. Efficiently interfers with late stages of cell wall biosynthesis leading to accumulation of the soluble peptidoglycan precursor UDP-N-acetylmuramic acid-pentapeptide (UDP-MurNAc-pentapeptide) in the cytoplasm. Slightly higher activity than NAI-107 against multidrug-resistant Gram-positive pathogens.
宿主来源:
Isolated from Actinoallomurus sp.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
2293.4 (A1; R=OH)2277.4 (A2; R=H)
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>80% (HPLC, for A1/A2)
CAS号:
1820892-86-1
分子式:
C94H127BrN26O27S5 (A1) C94H127BrN26O26S5 (A2)
溶解度:
Soluble in DMSO, aqueous acetonitrile or ethanol.
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