深圳欣博盛生物科技有限公司 a1

Nanog-TAT Recombinant Protein
品牌:ProSci LLC
货号:40-526-0.005 mg 规格:0.005 mg 目录价:¥3783
货号:40-526-0.02 mg 规格:0.02 mg 目录价:¥5674.5
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Nanog-TAT Recombinant Protein
别名:
PN8, NANOG, NANOGP1, Putative homeobox protein NANOGP8
表达系统:
E. coli
保存温度:
The lyophilized Nanog-TAT recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted Nanog-TAT is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing Nanog-TAT recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
运输温度:
Blue Ice
产品形式:
Lyophilized
产地:
美国
生产商:
Prosci
功能与背景:
Nanog is a regulatory protein that is associated with undifferentiated pluripotent cells. The expression of Nanog, which is suppressed in all adult tissues, is restricted to embryonic stem cells and to certain pluripotent cancer cells. Decreased expression of Nanog is strongly correlated with cell differentiation. Nanog, most likely, acts as an intracellular regulator, which helps maintain pluripotency and self renewal via a STAT3 independent pathway. The introduction of Nanog, along with Sox2, Oct4, Lin28, into primary human fibroblasts was sufficient to confer a pluripotent state upon the fibroblast genome. The reprogrammed cells thus obtained resemble ESC in morphology and gene expression. Protein transduction using TAT fusion proteins represents an alternative methodology for introducing transcription factors into primary as well as transformed cells. Recombinant human Nanog-TAT is a 36.1 kDa protein, which is synthesized as a 304 amino acid polypeptide plus a 13- residue C-terminal TAT peptide.
纯度:
Greater than 95% by SDS-PAGE gel and HPLC analyses.
生物活性:
Endotoxin level is less than 0.1 ng per ug (1EU/μg).
Accession #:
Q6NSW7
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