Nectin-2 Recombinant Protein-其他重组蛋白-深圳欣博盛生物科技有限公司

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Nectin-2 Recombinant Protein

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：96-928

规格：0.1 mg

目录价：￥9038

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Nectin-2 Recombinant Protein

别名:

CD112,Nectin-2,PVRL2

实验应用:

ELISA,WB

表达系统:

HEK293 cells

保存温度:

Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.

运输温度:

Blue Ice

产品形式:

Lyophilized

存储溶液:

Tris with Glycine, Arginine and NaCl, pH7.5

产地:

美国

生产商:

Prosci

功能与背景:

Poliovirus receptor-related 2 (PVRL2) is also known as nectin-2 and CD112 (formerly herpesvirus entry mediator B, HVEB), which is a human plasma membrane glycoprotein. PVRL2 is one of the plasma membrane components of adherens junctions. PVRL2 also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in PVRL2 gene have been associated with differences in the severity of multiple sclerosis. Also, PVRL2 binds with low affinity to TIGIT. Furthermore, PVRL2 acts as a receptor for herpes simplex virus 1 (HHV-1) mutant Rid1, herpes simplex virus 1 (HHV-2) and pseudorabies virus (PRV).

纯度:

>95% as determined by SDS-PAGE.

Endotoxin level is less than 1.0 EU per ug by the LAL method.

生物活性:

Measured by its binding ability in a functional ELISA. Immobilized Human CD112, Fc Tag at 10 ug/mL (100 uL/well) can bind Biotinylated Human TIGIT, His Tag with a linear range of 0.6-5 ug/mL.

Accession #:

AAH03091

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