Nectin-3 Recombinant Protein-其他重组蛋白-深圳欣博盛生物科技有限公司

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Nectin-3 Recombinant Protein

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：96-930

规格：0.1 mg

目录价：￥9477

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Nectin-3 Recombinant Protein

别名:

CD113,Nectin-3,PVRL3

实验应用:

ELISA,WB

表达系统:

HEK293 cells

保存温度:

Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.

运输温度:

Blue Ice

产品形式:

Lyophilized

存储溶液:

Tris with Glycine, Arginine and NaCl, pH7.5

产地:

美国

生产商:

Prosci

功能与背景:

Poliovirus receptor-related 3 (PVRL3), also known as nectin-3 and CD113, is a human protein of the immunoglobulin superfamily which forms part of adherens junctions. Nectins are immunoglobulin-like adhesion molecules that interact with afadin (AF6; MIM 159559). Afadin is an actin filament-binding protein that connects nectins to the actin cytoskeleton. The nectin-afadin system organizes adherens junctions cooperatively with the cadherin system in epithelial cells. PVRL3 plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with PVRL2/nectin-2 at Sertoli-spermatid junctions. Furthermore, PVRL3 induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation.

纯度:

>95% as determined by SDS-PAGE.

Endotoxin level is less than 1.0 EU per ug by the LAL method.

生物活性:

Measured by its binding ability in a functional ELISA. Immobilized Human CD113, Fc Tag at 10 ug/mL (100 uL/well) can bind Biotinylated Human TIGIT, His Tag with a linear range of 0.3-5 ug/mL.

Accession #:

Q9NQS3

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