Neratinib-其他小分子化合物-深圳欣博盛生物科技有限公司

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Neratinib

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：CDX-N0326-M050	规格：50 mg	目录价：￥1470
货号：CDX-N0326-M100	规格：100 mg	目录价：￥2212
货号：CDX-N0326-M250	规格：250 mg	目录价：￥4424

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Neratinib

别名:

HKI-272

产品描述:

Neratinib is a cell-permable, irreversible, selective inhibitor of the HER2 kinase (IC50=59nM) and EGFR (IC50=92nM) by preventing phosphorylation of these proteins by their respective kinases. It also potently inhibits several mutants of HER2 and shows 10-fold or greater selectivity over a wide variety of other kinases. As an irreversible inhibitor, neratinib may circumvent acquired resistance developed against reversible inhibitors, including gefitinib. Neratinib displays activity against a variety of cancer cell lines, including A431, 3T3, and MDA-MB-435. Neratinib has been evaluated in clinical trials against cancers characterized by HER2 overexpression or HER2 activating mutations.

保存温度:

+4°C

运输温度:

Ambient

预期分子量:

557

产品形式:

solid

产地:

瑞士

纯度:

>98%