官网链接
折扣/货期| 货号：CDX-N0326-M050 | 规格：50 mg | 目录价：￥1470 |
| 货号：CDX-N0326-M100 | 规格：100 mg | 目录价：￥2212 |
| 货号：CDX-N0326-M250 | 规格：250 mg | 目录价：￥4424 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Neratinib
别名:
HKI-272
产品描述:
Neratinib is a cell-permable, irreversible, selective inhibitor of the HER2 kinase (IC50=59nM) and EGFR (IC50=92nM) by preventing phosphorylation of these proteins by their respective kinases. It also potently inhibits several mutants of HER2 and shows 10-fold or greater selectivity over a wide variety of other kinases. As an irreversible inhibitor, neratinib may circumvent acquired resistance developed against reversible inhibitors, including gefitinib. Neratinib displays activity against a variety of cancer cell lines, including A431, 3T3, and MDA-MB-435. Neratinib has been evaluated in clinical trials against cancers characterized by HER2 overexpression or HER2 activating mutations.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
557
产品形式:
solid
产地:
瑞士
纯度:
>98%
CAS号:
698387-09-6
分子式:
C30H29ClN6O3
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