货号:AG-CN2-0020-M005 | 规格:5 mg | 目录价:¥720 |
货号:AG-CN2-0020-M025 | 规格:25 mg | 目录价:¥2160 |
产品详情
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产品名称:
Nigericin . sodium salt
别名:
Antibiotic K 178; Helexin C; Polyetherin A; BRN 1696755; Azalomycin M; Antibiotic X-464
产品描述:
Antibiotic [1]. High affinity ionophore for monovalent cations such as H+, K+, Na+, Pb2+ [2, 3, 4, 7, 10]. Shows antibacterial (Gram-positive), antifungal, antitumor and antiviral activity [3, 6]. Disrupts membrane potential of mitochondria [2]. NLRP3/NALP3 activator. Signals through pannexin-1 to induce caspase-1 maturation and IL-1beta processing and release [5, 8, 11, 12]. Autophagy modulator [13]
宿主来源:
Isolated from Streptomyces hygroscopicus.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
724.0 . 23.0
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C. Store solutions at -20°C in the dark.
产地:
瑞士
纯度:
>98% (TLC)
CAS号:
28643-80-3
分子式:
C40H67O11 . Na
溶解度:
Soluble in methanol, ethanol, dichlormethane or ethyl acetate. Insoluble in water.
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