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折扣/货期| 货号：AG-CN2-0021-M001 | 规格：1 mg | 目录价：￥480 |
| 货号：AG-CN2-0021-M005 | 规格：5 mg | 目录价：￥1920 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Radicicol
别名:
Monorden; NSC 294404; RHI-12648
产品描述:
Antibiotic [1]. Protein tyrosine kinase inhibitor [1]. Has antifungal [4], antimalarial [6], antiangiogenic (in vivo) [2], anti-inflammatory [5] and antiviral activity. Cyclooxygenase-2 (COX-2) expression inhibitor without affecting COX-1 expression in LPS-stimulated macrophages [3, 5]. Induces the differentiation of HL-60 cells into macrophages [4]. Potent HSP90 inhibitor [7, 9, 12]. Anticancer compound [7, 9, 12]. In vivo Rad/Raf interaction inhibitor [8]. Inhibitor of AP-1-, NF-kappaB- and serum response factor (SRF)-mediated transcription. Suppresses expression of iNOS (NOS II) [10]. Non-competitive inhibitor of ATP citrate lyase [11]. DNA topoisomerase VI and type II DNA topoisomerase inhibitor [13]. Protects against LPS/IFN-gamma-induced neuronal cell death [14]. Apoptosis inducer [16]. Pyruvate dehydrogenase kinase 3 (PDK3) inhibitor, by binding directly to the ATP-binding pocket [15].
宿主来源:
Isolated from Gilmaniella sp.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
364.8
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C. Store solutions at -20°C in the dark.
产地:
瑞士
纯度:
>99% (HPLC)
CAS号:
12772-57-5
分子式:
C18H17ClO6
溶解度:
Soluble in DMSO, methanol, acetone, ethyl acetate or chloroform.
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