NKCC2 Antibody: HRP-多抗-深圳欣博盛生物科技有限公司

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NKCC2 Antibody: HRP

品牌：Stressmarq

官网链接

说明书

折扣/货期

货号：SPC-401D-HRP

规格：100 µg

目录价：￥4901.4

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

NKCC2 Antibody: HRP

别名:

SLC12A1 Antibody, sodium potassium chloride cotransporter 2 Antibody, sodium-potassium-chloride cotransporter isoform 2 Antibody, BSC1 Antibody, MBSC1 Antibody, Na-K-2Cl cotransporter Antibody, NKCC2A variant A Antibody, RBSC Antibody

产品描述:

Rabbit Anti-Rat NKCC2 Polyclonal

反应种属:

Human | Mouse | Rat

宿主来源:

Rabbit

实验应用:

WB | IHC

靶标/特异性:

Detects ~160kDa.

推荐稀释度:

WB (1:1000); IHC (1:25); optimal dilutions for assays should be determined by the user.

免疫原:

Produced against a synthetic peptide mapping to a segment (amino acids 33-55) of the N-terminal tail of rat NKCC2 (antibody desgination L224).

免疫原种属:

Rat

克隆性:

Polyclonal

纯化方式:

Protein A Purified

偶联:

HRP

产品浓度:

1 mg/ml

保存温度:

Conjugated antibodies should be stored according to the product label

运输温度:

Blue Ice or 4ºC

存储溶液:

PBS, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated

产地:

加拿大

功能与背景:

NKCC2, a kidney-specific member of the cation chloride co-transporter family SLC12, facilitates transport of sodium, potassium, and chloride ions from the lumen of the renal thick ascending limb into the cell (1, 2). Transport of sodium dilutes the luminal fluid, decreasing its osmolality creating an osmotic driving force for water reabsorption in the connecting tubule and cortical collecting duct under the influence of the hormone vasopressin. NKCC2 is found on the apical surface of the thick ascending limb of the loop of Henle and is blocked by loop diuretics such as furosemide (1).

Accession #:

NP_001257546.1