Orlistat-其他小分子化合物-深圳欣博盛生物科技有限公司

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Orlistat

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-CN2-0050-M050	规格：50 mg	目录价：￥询价
货号：AG-CN2-0050-M250	规格：250 mg	目录价：￥询价

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Orlistat

别名:

Tetrahydrolipstatin; Xenical; Alli; Ro-18-0647

产品描述:

Hypolipemic cell permeable and irreversible pancreatic, gastric and carboxylester lipase inhibitor [1-3]. Anti-obesity and antihypercholesterolemic compound [2, 5, 11]. Antitumor compound by inhibition of the thioesterase domain of fatty acid synthase (FASN) [4, 6, 9, 10]. Anti-proliferative [4, 6, 9, 10]. Causes cell cycle arrest at G1 phase. Apoptosis inducer through caspase-3 activation [6, 10]. Sn-1-selective-diacylglycerol lipases alpha (DAGLalpha) inhibitor. Targets serine hydrolases in the nervous system, such as diacylglycerol lipase (DAGL), which is responsible for the conversion of DAG to 2-AG [7]. Partially inhibits the hydrolysis of triglycerides and lowers the absorption of dietary fat, promoting weight loss [8]. Promotes the sensitivity to TRAIL in cancer cells by ROS-mediated pathways [11].

宿主来源:

Synthetic. Originally isolated from Streptomyces sp.

保存温度:

+4°C

运输温度:

Ambient

预期分子量:

495.7

产品形式:

solid

产地:

瑞士