| 货号:40-571-0.01 mg | 规格:0.01 mg | 目录价:¥3783 |
| 货号:40-571-0.05 mg | 规格:0.05 mg | 目录价:¥5674.5 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Osteonectin Recombinant Protein
别名:
ON, ON, SPARC, Basement-membrane protein 40, BM-40
表达系统:
CHO cells
保存温度:
The lyophilized Osteonectin recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted Osteonectin stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing Osteonectin recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
运输温度:
Blue Ice
产品形式:
Lyophilized
产地:
美国
生产商:
Prosci
功能与背景:
SPARC/Osteonectin is a secreted, evolutionarily conserved collagen-binding glycoprotein that is involved in a variety of cellular activities. It is highly expressed in tissues undergoing morphogenesis, remodeling and wound repair. SPARC/Osteonectin and its related peptides bind to numerous proteins of the extracellular matrix (ECM), affect ECM protein expression, influence cellular adhesion and migration, and modulate growth factor-induced cell proliferation and angiogenesis. SPARC/Osteonectin consists of three domains; an N-terminal acidic region that binds calcium ions with low affinity, a module containing two EF-hand motifs that bind calcium with high affinity, and a cysteine-rich follistatin-like domain. Recombinant human SPARC/Osteonectin is a glycoprotein containing 286 amino acids that migrates at an apparent MW of 43.7 kDa by SDS-PAGE analysis due to the effect of glycosylation.
纯度:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
生物活性:
Biological activity was determined by its ability to inhibit alkaline phosphatase activity in differentiating MC3T3 cells using a concentration of IC50 0.5-0.7 μg/mL. Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Accession #:
NP_003109.1
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