官网链接
折扣/货期| 货号：IAX-700-104-L001 | 规格：1 ml | 目录价：￥3192 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Oxyresveratrol Sterile Solution
别名:
Oxyresveratrol LipodisqTM Sterile Solution; trans-2',3,4',5-Tetramethoxystilbene
产品描述:
Oxyresveratrol Lipodisq Sterile Solution is a ready-to-use nano-formulated aqueous solution. Oxyresveratrol is a naturally occurring analog of resveratrol. Potent antioxidant and free-radical scavenger. Shown to have neuroprotective activity against cerebral ischemia and against traumatic injury. Apoptosis inhibitor in transient cerebral ischemia. Inhibits viral DNA replication and late viral protein synthesis. Has depigmenting effects by effectively inhibiting tyrosinase activity, which catalyzes the rate-limiting step in synthesizing melanin pigments. Has anti-inflammatory properties based on inhibition of iNOS expression through down-regulation of NF-kB binding activity and significant inhibition of COX-2 activity. Anti-hyperlipidemic agent. Oxyresveratrol Lipodisq is based on a nanoparticle (11-40nm) drug delivery system comprising a discoidal phospholipid bilayer membrane stabilized by a chaperone molecule annulus. Internal properties of the phospholipid membrane support the disposition and stabilization of drug molecule candidates and preserve the native conformation of membrane molecules. The resulting encapsulated actives are rendered water-soluble and specialized for intra-cellular penetration/delivery via endosomal uptake mechanisms. Lipodisq solutions show a good safety profile and are suitable for in vitro and in vivo investigations.
产品浓度:
1mg/ml (0.1% w/vol)
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
244.2
产品形式:
liquid
存储溶液:
Liquid, detergent-free discoidal nano-formulation made of styrene-maleic acid lipid particles (SMALP), lecithin and sterile water.
产地:
瑞士
纯度:
>95% (HPLC)
生物活性:
Discoidal nano-particles can incorporate hydrophobic, poorly water-soluble compounds, such as lipids, lipoproteins and glycolipids. - Cell culture tested (human macrophage cell line) (MTT). - Recommended starting dilution: 1:200 or higher. - Optimal working concentrations depend on the applications and need to be determined. - Published procedures using Lipodisq formulations (Curcumin and IAXO TLR4 antagonists) in vivo rodent models at 3-10mg/kg. Recommended route of administration is subcutaneous (s.c.) with oral or nasal application as a possible alternative, which needs to be optimized.
分子式:
C14H12O4
促销活动
精品推荐
复制QQ号成功，请打开QQ后添加好友进行咨询