p53 Antibody-多抗-深圳欣博盛生物科技有限公司

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p53 Antibody

品牌：Stressmarq

官网链接

说明书

折扣/货期

货号：SPC-682D

规格：100 µg

目录价：￥4258.8

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

p53 Antibody

别名:

TP53 Antibody, Tumor Protein 53 Antibody, BCC7 Antibody, LFS1 Antibody, TRP53 Antibody, p53 tumor suppressor Antibody

产品描述:

Rabbit Anti-Human p53 Polyclona

反应种属:

Human

宿主来源:

Rabbit

实验应用:

WB | ICC/IF

靶标/特异性:

Predicted molecular weight at ~43.7kDa. Observed bands at ~53kDa.

推荐稀释度:

WB (1:1000); ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

免疫原:

Synthetic peptide from the C-terminal of human tumor protein p53.

免疫原种属:

Human

克隆性:

Polyclonal

纯化方式:

Peptide Affinity Purified

偶联:

Unconjugated

产品浓度:

1 mg/ml

保存温度:

-20ºC

运输温度:

Blue Ice or 4ºC

存储溶液:

PBS, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated

产地:

加拿大

功能与背景:

The p53 protein (tumor protein 53 or TP53) is a DNA-binding cell cycle-regulating transcription factor that governs cell division and the fine balance between cell death and cell survival (1). P53 plays a critical role in tumor suppression and hence it is often described as "the guardian of the genome", "the guardian angel gene", or the "master watchman." This also refers to its role in conserving stability by preventing genome mutation (2). Defects in p53 are linked to >50% of human cancers, and restoring p53 function to these cancer cells can induce growth arrest and apoptosis (3). When p53 has been damaged, it can also lead to autoimmune disorders (4, 5).

Accession #:

NP_000537.3