P7C3-其他小分子化合物-深圳欣博盛生物科技有限公司

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P7C3

品牌：Stressmarq

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说明书

折扣/货期

货号：SIH-571-25MG

规格：25 mg

目录价：￥4867.2

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

P7C3

别名:

1-(3,6-dibromo-9H-carbazol-9-yl)-3-(phenylamino)propan-2-ol; AK34095

产品描述:

NAMPT activator

保存温度:

-20ºC

运输温度:

Shipped Ambient

预期分子量:

474.2

产品形式:

Off-white powder

产地:

加拿大

功能与背景:

P7C3 exerts proneurogenic activity by protecting newborn neurons from apoptosis. Prolonged administration to aged rats impedes neuronal death and preserves cognitive capacity (1). Delays disease progression in G93A-SOD2 mutant mouse model of amyotrophic lateral sclerosis (2). Blocks MPTP-mediated cell death of dopaminergic neurons in the substantia nigra of adult mice, a model of Parkinson's disease (3). Restores hippocampal neurogenesis in a mouse model of Down Syndrome (4). The mechanism of action involves activation of nicotinamide phosphoribosyltransferase (NAMPT) with concomitant increase of intracellular levels of NAD (5). Active in vivo.

纯度:

>98% (TLC); NMR (Conforms)

来源:

Synthetic

CAS号:

301353-96-8

分子式:

C21H18Br2N2O

溶解度:

May be dissolved in DMSO (40 mg/ml)

PubChem CID:

2836187