PD-L1 / B7-H1 (19-134) Recombinant Protein-其他重组蛋白-深圳欣博盛生物科技有限公司

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PD-L1 / B7-H1 (19-134) Recombinant Protein

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：11-114

规格：0.1 mg

目录价：￥10126

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

PD-L1 / B7-H1 (19-134) Recombinant Protein

别名:

PD-L1,CD274,B7-H1,PDCD1L1,PDCD1LG1

实验应用:

ELISA,WB

表达系统:

HEK293 cells

保存温度:

Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.

运输温度:

Blue Ice

产品形式:

Lyophilized

存储溶液:

PBS, pH7.4

产地:

美国

生产商:

Prosci

功能与背景:

Programmed cell death 1 ligand 1 (PD-L1) is also known as cluster of differentiation (CD274) or B7 homolog 1 (B7-H1), is a member of the growing B7 family of immune molecules and is involved in the regulation of cellular and humoral immune responses. B7-H1 is a cell surface immunoglobulin superfamily with two Ig-like domains within the extracellular region and a short cytoplasmic domain. PD-L1 is highly expressed in the heart, skeletal muscle, placenta and lung and weakly expressed in the thymus, spleen, kidney and liver. PD-L1 is expressed on activated T-cells, B-cells, dendritic cells, keratinocytes and monocytes. PD-L1 is up-regulated on T- and B-cells, dendritic cells, keratinocytes and monocytes after LPS and IFNG activation and up-regulated in B-cells activated by surface Ig cross-linking. PD-L1 involve in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner.

纯度:

>95% as determined by SDS-PAGE.

Accession #:

NP_054862.1

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