LAG3 Detection Set -其他-深圳欣博盛生物科技有限公司

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LAG3 Detection Set

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：SD8700

规格：1 Set

目录价：￥6420.375

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

LAG3 Detection Set

反应种属:

Human

宿主来源:

llama

实验应用:

ELISA,IHC-P,IF,Flow

同种型:

sdab

克隆性:

Monoclonal

纯化方式:

LAG3 Antibodies are affinity chromatography purified via Nickel column. Antibodies are supplied as a His-tagged purified protein. They also contains a myc-tag for detection.

偶联:

Unconjugated

产品浓度:

Antibody 1 mg/mL

保存温度:

LAG3 antibodies should be stored in working aliquots at -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

运输温度:

Dry Ice

产品形式:

Liquid

存储溶液:

LAG3 Antibodies are supplied in PBS.

产地:

美国

生产商:

Prosci

功能与背景:

The lymphocyte activation gene-3 (LAG3) is a member of the immunoglobulin superfamily and binds MHC class II with high affinity (1), negatively regulating T-cell function and homeostasis (2). It is expressed in B, T, and NK cells, monocytes, and dendritic cells (3), and acts to regulate T cell expansion (4). LAG3 is also an important immune checkpoint protein, with anti-LAG3 antibodies activating T effector cells and affecting regulatory T cell functions. Furthermore LAG3 appears to act in a synergistic fashion with PD-1/PD-L1, suggesting that a dual antibody approach may prove useful in cancer immunotherapy.

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