| 货号:SPC-149F | 规格:400 µl | 目录价:¥4384.8 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Phosphoserine Antibody
别名:
Phospho-ser Antibody, pS Antibody, pSer Antibody, Phospho-serine antibody
产品描述:
Rabbit Anti-Phosphoserine Polyclonal
反应种属:
Species Independent
宿主来源:
Rabbit
实验应用:
WB | IHC | ICC/IF | IP | ELISA
靶标/特异性:
Detects proteins phosphorylated on serine residues. Does not cross-react with phosphotyrosine.
推荐稀释度:
WB (1:500), ICC/IF (1:50), ELISA (1:250), IP (1:100); optimal dilutions for assays should be determined by the user.
免疫原:
Phosphoserine conjugated to KLH, and phosvitin mixture
克隆性:
Polyclonal
纯化方式:
Peptide Affinity Purified
偶联:
Unconjugated
产品浓度:
0.25 mg/ml
保存温度:
-20ºC
运输温度:
Blue Ice or 4ºC
存储溶液:
PBS, 50% glycerol, 0.01% sodium azide *Storage buffer may change when conjugated
产地:
加拿大
功能与背景:
Protein phosphorylation is an important posttranslational modification that serves many key functions to regulate a protein's activity, localization, and protein-protein interactions. Phosphorylation is catalyzed by various specific protein kinases, which involves removing a phosphate group from ATP and covalently attaching it to to a recipient protein that acts as a substrate. Most kinases act on both serine and threonine; others act on tyrosine, and a number (dual specificity kinases) act on all three. Because phosphorylation can occur at multiple sites on any given protein, it can therefore change the function or localization of that protein at any time (1). Changing the function of these proteins has been linked to a number of diseases, including cancer, diabetes, heart disease, inflammation and neurological disorders (2-4).
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