PSME3 Recombinant Protein-其他重组蛋白-深圳欣博盛生物科技有限公司

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PSME3 Recombinant Protein

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：96-941

规格：0.1 mg

目录价：￥6494

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

PSME3 Recombinant Protein

别名:

PSME3,PA28gamma,REG-gamma

实验应用:

表达系统:

E. coli

保存温度:

Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.

运输温度:

Blue Ice

产品形式:

Lyophilized

存储溶液:

50 mM Tris, 150 mM NaCl, pH7.5

产地:

美国

生产商:

Prosci

功能与背景:

Proteasome activator complex subunit 3 (PSME3),a member of the PA28 family, is also known as 11S regulator complex subunit gamma (REG-gamma), activator of multicatalytic protease subunit 3 and proteasome activator 28 subunit gamma (PA28gamma). PSME3 activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. PSME3 can also facilitate the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. Furthermore,PSME3 may also be involved in cell cycle regulation.

纯度:

>95% as determined by SDS-PAGE.

Endotoxin level is less than 1.0 EU per ug by the LAL method.

Accession #:

NP_00578

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