| 货号:CDX-P0234-M010 | 规格:10 mg | 目录价:¥924 |
| 货号:CDX-P0234-M100 | 规格:100 mg | 目录价:¥2030 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Pterostilbene
别名:
trans-3,5-Dimethoxy-4'-Hydroxystilbene; 4-[(1E)-2-(3,5-Dimethoxyphenyl)ethenyl]phenol; 3',5'-Dimethoxy-4-Stilbenol
产品描述:
Cell permeable natural methoxylated analog of resveratrol. Antioxidant, antiproliferative, anti-inflammatory, anti-hyperglycemic and anti-diabetic agent. Induces apoptosis. Induces Autophagy. Pterostilbene is a naturally-occurring dimethyl ether analog of resveratrol that is abundant in blueberries. Like resveratrol, pterostilbene acts as a powerful antioxidant, suppresses the synthesis of prostaglandin E2 from lipopolysaccharide-stimulated human peripheral blood mononuclear cells (IC50 = 1.0 µM for pterostilbene, 3.2 µM for resveratrol), and inhibits cell proliferation (IC50 = ~60 µM for both compounds). Very potent inhibitor of cytochrome P450 1A1 (CYP1A1) with Ki=0.57µM. Pterostilbene blocks the activation of ERK1/2, p38 MAPK, and PI3K/Akt signaling pathways, reducing NF-kappaB and AP-1 transcriptional activation. Moderately inhibits COX-1 and COX-2 (IC50=19.8µM and 83.9µM).
宿主来源:
Synthetic.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
256.3
产品形式:
solid
产地:
瑞士
纯度:
>97% (HPLC)
CAS号:
537-42-8
分子式:
C16H16O3
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