| 货号:CDX-R0014-M005 | 规格:5 mg | 目录价:¥1134 |
| 货号:CDX-R0014-M010 | 规格:10 mg | 目录价:¥1750 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Resorufin benzyl ether
别名:
Benzyloxyresorufin; 7-Benzyloxyresorufin; O7-Benzylresorufin; 7-Benzyloxy-3H-phenoxazin-3-one
产品描述:
Resorufin benzyl ether (7-Benzyloxyresorufin) is a fluorogenic substrate widely used for monitoring cytochrome P450 (CYP450) activities in cell extracts and solutions. It is the model substrate for 7-Benzoxyresorufin-O-dealkylase (BROD) assays. It is typically used near its apparent Km value of 30 �M to screen the inhibition/activation potential of test compounds, to predict potential drug-drug interactions, or to monitor other CYP450 activities. Cytochrome P450 oxidase is a large number of evolutionary related oxidative enzymes important in animal, plant, and bacterial physiology. Most cytochromes P450 (CYPs) have about 500 amino acids and a heme group at the active site. Upon enzymatic cleavage of 7-Benzyloxyresorufin by CYP450, the fluorescent hydrolysis product resorufin is released and its fluorescence can be used to quantify enzyme activity. Spectral data of Resorufin: lambdaex=571nm, lambdaem=585nm.
宿主来源:
Synthetic
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
303.31
产品形式:
solid
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
87687-02-3
分子式:
C19H13NO3
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