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折扣/货期| 货号：AG-CR1-3645-M005 | 规格：5 mg | 目录价：￥480 |
| 货号：AG-CR1-3645-M025 | 规格：25 mg | 目录价：￥1140 |
| 货号：AG-CR1-3645-M100 | 规格：100 mg | 目录价：￥2160 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Ruxolitinib . phosphate salt
别名:
INCB018424; INC 424
产品描述:
Water-soluble phosphate salt of Ruxolitinib. Antineoplastic, anti-inflammatory and immunomodulating agent. Orally bioavailable potent ATP mimetic that inhibits both JAK1 and JAK2 with IC50 values of 2.7 and 4.5nM, respectively and is less selective for JAK3 (IC50=322nM). Affects DC differentiation and function, leading to impaired T cell activation. Used in the treatment of myeloproliferative neoplasms and psoriasis. Anticancer agent. Shown to induce apoptosis and autophagy. Potent and selective inhibitor of HIV-1 replication and virus reactivation in vitro. It is investigated against the spread of the SARS-CoV-2 (COVID-19).
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
306.4 . 98.0
产品形式:
solid
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
1092939-17-7
分子式:
C17H18N6 . H3O4P
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