SOD (EC) Antibody: ATTO 390-单抗-深圳欣博盛生物科技有限公司

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SOD (EC) Antibody: ATTO 390

品牌：Stressmarq

官网链接

说明书

折扣/货期

货号：SMC-167D-A390

规格：100 µg

目录价：￥4851

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

SOD (EC) Antibody: ATTO 390

别名:

EC SOD antibody, EC-SOD antibody, Extracellular superoxide dismutase [Cu Zn] antibody, Extracellular superoxide dismutase [Cu-Zn] antibody, Extracellular superoxide dismutase antibody, Extracellular superoxide dismutase precursor antibody, MGC20077 antibody, SOD 3 antibody, SOD3 antibody, SODE_HUMAN antibody, Superoxide dismutase 3 extracellular antibody

产品描述:

Mouse Anti-Human SOD (EC) Monoclonal IgG1 Kappa

反应种属:

Human | Mouse | Rat | Guinea Pig (Cavia porcellus)

宿主来源:

Mouse

实验应用:

WB | IHC | ICC/IF | ELISA

靶标/特异性:

Detects extracellular SOD ~35kDa.

同种型:

IgG1 Kappa

推荐稀释度:

WB (1:1000), IHC (1:100), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

免疫原:

Human extracellular SOD purified from aortas

免疫原种属:

Human

克隆性:

Monoclonal

克隆号:

4GG11G6

纯化方式:

Protein G Purified

偶联:

ATTO 390

产品浓度:

1 mg/ml

保存温度:

Conjugated antibodies should be stored according to the product label

运输温度:

Blue Ice or 4ºC

存储溶液:

PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated

产地:

加拿大

功能与背景:

Superoxide dismutase (SOD) is an endogenously produced intracellular enzyme present in almost every cell in the body (3). It works by catalyzing the dismutation of the superoxide radical O2ˉ to O2 and H2O2, which are then metabolized to H2O and O2 by catalase and glutathione peroxidase (2, 5). In general, SODs play a major role in antioxidant defense mechanisms (4). There are three types of SOD in mammalian cells. One form (SOD1) contains Cu and Zn ions as a homodimer and exists in the cytoplasm. The two subunits of 16 kDa each are linked by two cysteines forming an intra-subunit disulphide bridge (3). The second form (SOD2) is a manganese containing enzyme and resides in the mitochondrial matrix. It is a homotetramer of 80 kDa. The third form (SOD3 or EC-SOD) is like SOD1 in that it contains Cu and Zn ions, however it is distinct in that it is a homotetramer, with a mass of 30 kDA and it exists only in the extra-cellular space (6). SOD3 can also be distinguished by its heparin-binding capacity (1).

Accession #:

NP_003093.2