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折扣/货期| 货号：AG-CP3-0046-M001 | 规格：1 mg | 目录价：￥480 |
| 货号：AG-CP3-0046-M005 | 规格：5 mg | 目录价：￥1440 |
| 货号：AG-CP3-0046-M025 | 规格：25 mg | 目录价：￥3360 |
| 货号：AG-CP3-0046-M100 | 规格：100 mg | 目录价：￥10080 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Survodutide
别名:
BI-456906; EX-A7878; GTPL13383
产品描述:
Survodutide is a novel long-acting dual glucagon-like peptide-1 (GLP-1) receptor and glucagon receptor (GCGR) agonist. Survodutide potently activates the GLP-1R signaling pathway to stimulate glucose-dependent insulin secretion through activity at the GCG receptor (GCGR) or the GLP-1R. Survodutide is a synthetic peptide glucagon analog rather than an analog of oxyntomodulin, unlike other dual GLP-1/glucagon dual agonists. Survodutide binds human and mouse GCGR and GLP-1R and stimulates insulin secretion in isolated mouse, rat and perifused human pancreatic islets. Survodutide is used in studies of obesity and type 2 diabetes (T2D) and is designed enhancing energy expenditure and fat metabolism and decreasing food intake. Survodutide comprises a 29 amino acid linear synthetic peptide conjugated to a C18 fatty diacid moiety through a hydrophilic linker at the lysine residue at position 24. Due to this moiety, the compound is highly bound to albumin in the plasma which prolongs its half-life. It contains one non-coded amino acid residue (Ac4c, 1-Aminocyclobutane-1-carboxylic acid) at position 2, well established as the site of proteolytic activity for dipeptidyl peptidase-4.
宿主来源:
Synthetic.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
4231.7
产品形式:
solid
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
2805997-46-8
分子式:
C192H289N47O61
促销活动
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