| 货号:CDX-T0415-M005 | 规格:5 mg | 目录价:¥742 |
| 货号:CDX-T0415-M010 | 规格:10 mg | 目录价:¥1302 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Tangeretin
别名:
4',5,6,7,8-Pentamethoxyflavone; NSC 53909; NSC 618905; Ponkanetin; 5,6,7,8-Tetramethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
产品描述:
Tangeritin is a polymethoxylated flavone isolated from peels of citrus fruits with antiproliferative and antioxidant properties. It inhibits signaling in cancer cells, reducing ERK phosphorylation and growth of estradiol-stimulated T47D breast cancer cells and blocking p38 MAPK, JNK, and Akt activation in interleukin-1beta-stimulated human lung carcinoma A549 cells. It is described to block cell cycle progression at G1 and induce apoptosis. Shows anti-inflammatory, osteoprotective and neuroprotective effects. Tangeritin activates the pregnane X receptor, inducing MDR1 expression in human colonic LS180 cancer cells. Shown to be a Notch-1 inhibitor. Tangeretin stimulates glucose uptake via regulation of AMPK signaling pathways and has been shown to antagonize ABCB1-mediated multidrug resistance.
宿主来源:
Isolated from plant source.
保存温度:
+20°C
运输温度:
Ambient
预期分子量:
372.37
产品形式:
solid
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
481-53-8
分子式:
C20H20O7
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