| 货号:CDX-T0417-M005 | 规格:5 mg | 目录价:¥742 |
| 货号:CDX-T0417-M025 | 规格:25 mg | 目录价:¥2940 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Tanshinone I
别名:
Tanshinon I; Tanshinone A; 1,6-Dimethylphenanthro[1,2-b]furan-10,11-dione
产品描述:
Tanshinone I is a diterpene that has been found in S. miltiorrhiza and has diverse biological activities, including anticancer, antidiabetic, anti-inflammatory, immunosuppressive, anticoagulant and neuroprotective properties. It inhibits proliferation in a variety of cancer cell lines, including KB/VCR, MCF-7/ADR, and K562/A02 multidrug resistance cell lines. It inhibits topoisomerase I- and topoisomerase II-mediated supercoiled DNA relaxation activity. It has been shown to induce apoptosis in several cancer cell lines. It reduces plasma levels of total cholesterol, triglycerides, LDL and nonesterified fatty acids and decreases blood glucose levels in a rat model of type 2 diabetes induced by streptozotocin and a high-fat diet. Tanshinone I reduces the LPS-induced expression of TNF-alpha, IL-1beta, and IL-6 in microglia in vitro. It is neuroprotective in a mouse model of Parkinson‘s disease induced by MPTP.
宿主来源:
Isolated from plant source.
保存温度:
+20°C
运输温度:
Ambient
预期分子量:
276.29
产品形式:
solid
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
568-73-0
分子式:
C18H12O3
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