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折扣/货期| 货号：SPC-802D-HRP | 规格：100 µg | 目录价：￥4750.2 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Tau Antibody: HRP
别名:
Tau Antibody, Neurofibrillary tangle protein Antibody, MAPTL Antibody, Microtubule-associated protein tau Antibody, MTBT1 Antibody, Paired helical filament-tau Antibody, TAU Antibody, PHF-tau Antibody, MAPT Antibody, AI413597 antibody, AW045860 antibody, DDPAC antibody, FLJ31424 antibody, FTDP 17 antibody, G protein beta1/gamma2 subunit interacting factor 1 antibody, MAPT antibody, MAPTL antibody, MGC134287 antibody, MGC138549 antibody, MGC156663 antibody, Microtubule associated protein tau antibody, Microtubule associated protein tau isoform 4 antibody, Microtubule-associated protein tau antibody, MSTD antibody, Mtapt antibody, MTBT1 antibody, MTBT2 antibody, Neurofibrillary tangle protein antibody, Paired helical filament tau antibody, Paired helical filament-tau antibody, PHF tau antibody, PHF-tau antibody, PPND antibody, PPP1R103 antibody, Protein phosphatase 1, regulatory subunit 103 antibody, pTau antibody, RNPTAU antibody, TAU antibody, TAU_HUMAN antibody, Tauopathy and respiratory failure, included antibody
产品描述:
Rabbit Anti-Human Tau Polyclonal
反应种属:
Human | Mouse
宿主来源:
Rabbit
实验应用:
WB | ELISA | IHC
靶标/特异性:
Detects ~45.8kda.
推荐稀释度:
WB (1:1000); optimal dilutions for assays should be determined by the user.; optimal dilutions for assays should be determined by the user.
免疫原:
Recombinant Human Tau 2NR4 P301S Fibril
免疫原种属:
Human
克隆性:
Polyclonal
纯化方式:
Protein A Purified
偶联:
HRP
产品浓度:
1 mg/ml
保存温度:
Conjugated antibodies should be stored according to the product label
运输温度:
Blue Ice or 4ºC
存储溶液:
PBS pH 7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
产地:
加拿大
功能与背景:
Alzheimer’s Disease (AD) is the most common neurodegenerative disease, affecting 10% of seniors over the age of 65 (1). It was named after Alois Alzheimer, a German scientist who discovered tangled bundles of fibrils where neurons had once been in the brain of a deceased patient in 1907 (2). Tau (tubulin-associated unit) is normally located in the axons of neurons where it stabilizes microtubules. Tauopathies such as AD are characterized by neurofibrillary tangles containing hyperphosphorylated tau fibrils (3). There are six isoforms of tau in the adult human brain: three with four repeat units (4R) and three with three repeat units (3R) (4). K18 is a truncated form of human tau containing only the 4 microtubule binding repeats (5). P301L (PL) is a mutation where proline is replaced by leucine at codon 301 of tau, and has been linked to frontotemporal dementia (6).
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