| 货号:AG-CR1-3660-M005 | 规格:5 mg | 目录价:¥480 |
| 货号:AG-CR1-3660-M025 | 规格:25 mg | 目录价:¥1200 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
TBB
别名:
4,5,6,7-Tetrabromo-2-azabenzimidazole; Tetrabromobenzotriazole; NSC 231634; TBBt
产品描述:
ATP/GTP-competitive cell permeable casein kinase II (CK2) inhibitor (IC50=0.9µM for rat liver. Less potently inhibits CCK2/cyclin A, GSK3beta and phosphorylase kinase (IC50=15.6, 11.2 and 8.7µM, respectively). Binds to the Val66 residue of CK2 and inhibits the binding of ATP/GTP. Moderate DYRK1A inhibitor (IC50=4.4µM). Induces caspase-dependent apoptosis and degrades hematopoietic lineage cell-specific protein 1 (HS1) in Jurkat cells.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
434.7
产品形式:
solid
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
17374-26-4
分子式:
C6HBr4N3
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