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折扣/货期| 货号：SIH-526-50MG | 规格：50 mg | 目录价：￥3211.2 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Teprenone
别名:
Geranylgeranylacetone, GGA, 6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetraen-2-one
产品描述:
HSP70 Inducer
保存温度:
-20ºC
运输温度:
Shipped Ambient
预期分子量:
330.6
产品形式:
Colorless Oil
产地:
加拿大
功能与背景:
Teprenone can induce expression of HSP70, HSPB8, and HSPB1. Induction of HSP70 expression is protective against the development of various diseases, such as inflammatory bowel disease, hypoxic/ischemic brain injury and spinal and bulbar muscular atrophy (cytoprotective and anti-inflammatory effects) (1, 2). Reports indicate that Teprenone protects against NSAID-induced gastric and intestinal lesions by induction of HSP70 expression (2). Other studies have shown that it induces expression of HSPB8 and HSPB1 and reduces the formation of amyloid oligomers as well as insoluble aggregates in HSPB5 R120G TG mice (3, 4).
纯度:
>95% (GC)
来源:
Synthetic
CAS号:
6809-52-5
分子式:
C23H38O
溶解度:
Soluble in DMSO (30 mg/ml)
PubChem CID:
5282199
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