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折扣/货期| 货号：BVT-0477-M001 | 规格：1 mg | 目录价：￥660 |
| 货号：BVT-0477-M005 | 规格：5 mg | 目录价：￥2160 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Terreic acid
别名:
TA; (1R,6S)-3-hydroxy-4-methyl-7-oxabicyclo[4.1.0]hept- 3-ene-2,5-dione; (-)-Terreic acid
产品描述:
Mycotoxin. Antibacterial and anticancer agent. A cell-permeable quinone epoxide antibiotic. Covalent inhibitor of the bacterial enzyme UDP-N-acetylglucosamine 1-carboxyvinyltransferase (MurA), which catalyzes the first committed step of bacterial cell wall biosynthesis. More potent than the known MurA inhibitor Fosphomycin. Reversible, substrate competitive and selective inhibitor of Bruton's tyrosine kinase (BTK) catalytic activity, an important factor in B-cell and mast cell activation. Shown to bind to the BTK pleckstrin homology domain (BTK-PH) and block the interaction between the BTK-PH and PKC, affecting the catalytic activity of BTK but not of PKC. Has minimal effect on Lyn, Syk, PKA, casein kinase I, ERK1, ERK2, and p38 kinase activities. Antioxidant.
宿主来源:
Isolated from Aspergillus terreus.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
154.1
产品形式:
solid
有效期:
Stable for at least 1 year after receipt when stored at -20°C. Store solutions at -20°C in the dark.
产地:
瑞士
纯度:
>99% (HPLC)
CAS号:
121-40-4
分子式:
C7H6O4
溶解度:
Soluble in DMSO (10mg/ml), EtOH, MeOH, acetone, DCM or water (1mg/ml, warming and sonication might be necessary).
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