TIMP-2 Recombinant Protein-其他重组蛋白-深圳欣博盛生物科技有限公司

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TIMP-2 Recombinant Protein

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：96-957

规格：0.05 mg

目录价：￥8687.25

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

TIMP-2 Recombinant Protein

别名:

CSC-21K,TIMP2

实验应用:

表达系统:

HEK293 cells

保存温度:

Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.

运输温度:

Blue Ice

产品形式:

Lyophilized

存储溶液:

50 mM Tris, 150 mM NaCl, pH7.5

产地:

美国

生产商:

Prosci

功能与背景:

TIMP metallopeptidase inhibitor 2 is also known as TIMP2, which belongs to the protease inhibitor I35 (TIMP) family. This family protein are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The TIMP family encompasses four members (TIMP1, TIMP2, TIMP3, TIMP4), and they inhibit most MMPs by forming non-covalent binary complex. In addition to an inhibitory role against metalloproteinases, TIMP2 has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, TIMP-2 may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.

纯度:

>98% as determined by SDS-PAGE.

Endotoxin level is less than 1.0 EU per ug by the LAL method.

Accession #:

NP_003246.1

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