TLR4 Antibody: ATTO 390-多抗-深圳欣博盛生物科技有限公司

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TLR4 Antibody: ATTO 390

品牌：Stressmarq

官网链接

说明书

折扣/货期

货号：SPC-200D-A390

规格：100 µg

目录价：￥4485.6

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

TLR4 Antibody: ATTO 390

别名:

ARMD10 Antibody, CD284 Antibody, TLR 4 Antibody, TOLL Antibody, Toll like receptor 4 Antibody

产品描述:

Rabbit Anti-Human TLR4 Polyclonal

反应种属:

Human | Mouse

宿主来源:

Rabbit

实验应用:

WB | IHC | ICC/IF | FCM | FACS

靶标/特异性:

Detects ~75-80kDa when tested against partial recombinant mouse TLR4 (extra-cellular portion plus His-tag).

推荐稀释度:

WB (1:500), IHC (1:50); optimal dilutions for assays should be determined by the user.

免疫原:

Developed against a synthetic peptide corresponding to amino acids 420-435 of human TLR4

免疫原种属:

Human

克隆性:

Polyclonal

纯化方式:

Protein A Purified

偶联:

ATTO 390

产品浓度:

1 mg/ml

保存温度:

Conjugated antibodies should be stored according to the product label

运输温度:

Blue Ice or 4ºC

存储溶液:

PBS, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated

产地:

加拿大

功能与背景:

The Toll-like receptor (TLR) family in mammal comprises a family of trans-membrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and 1L-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules (1). The TLR family is a phylo-genetically conserved mediator of innate immunity that is essential for microbial recognition (2). Ten human homologs of TLRs (TLR1-10) have been described (3). Amount this family of receptors, TLR2 and TLR4 have been most studied. These studies have suggested that TLR2 and TLR4 may serve as potential main mediators of LPS signaling (4,5). The mouse TLR4 cDNA codes for a protein consisting of 839 amino acids, with an approximate molecular weight of 90kDa (6).

Accession #:

NP_612564.1