| 货号:40-275-0.005 mg | 规格:0.005 mg | 目录价:¥3783 |
| 货号:40-275-0.02 mg | 规格:0.02 mg | 目录价:¥5674.5 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
TNF beta Recombinant Protein
别名:
LT, TNFB, TNFSF1, Lymphotoxin-alpha, TNF-beta, LT-alpha
表达系统:
E. coli
保存温度:
The lyophilized TNF beta recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted TNF beta is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing TNF beta recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
运输温度:
Blue Ice
产品形式:
Lyophilized
产地:
美国
生产商:
Prosci
功能与背景:
TNF-β is a potent mediator of inflammatory and immune responses. It belongs to the TNF family of ligands and signals through TNFR1 and TNFR2. TNF-β is produced by activated T and B lymphocytes, and has similar activities to TNF-alpha. Like TNF-α, TNF-β is involved in the regulation of various biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, coagulation, and neurotransmission. TNF-β is secreted as a soluble polypeptide, but can form heterotrimers with lymphotoxin-β, which effectively anchors the TNF-β to the cell surface. TNF-β is cytotoxic to a wide range of tumor cells. Recombinant human TNF-β is a secreted 171 amino acid protein (18.6 kDa) which forms an active non-disulfide linked homotrimer structure in solution.
纯度:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
生物活性:
The ED50 was determined by the cytolysis of murine L929 cells in the presence of Actinomycin - D is ≤ 0.05 ng/mL, corresponding to a specific activity of ≥ 2 x 107 units/mg.
Accession #:
NP_000586.2
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