TNF-R1 Antibody: FITC-多抗-深圳欣博盛生物科技有限公司

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TNF-R1 Antibody: FITC

品牌：Stressmarq

官网链接

说明书

折扣/货期

货号：SPC-170D-FITC

规格：100 µg

目录价：￥4548.6

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

TNF-R1 Antibody: FITC

别名:

Tumor necrosis factor receptor 1 Antibody, TNFR-1 Antibody, TNFRSF1A Antibody, TNFAR Antibody, TNFR1 Antibody

产品描述:

Rabbit Anti-Mouse TNF-R1 Polyclonal

反应种属:

宿主来源:

Rabbit

实验应用:

WB | IHC | ICC/IF | IP

靶标/特异性:

Detects ~55kDa. Other bands present may be the result of oligomerization, self-aggregation and/or cleavage of the TNF-R1 extracellular domain.

推荐稀释度:

WB (1:1000), IHC (1:100), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

免疫原:

Peptide corresponding to AA 20-43 of the mouse TNF-R1 sequence, identical to rat and human over those residues

免疫原种属:

Mouse

克隆性:

Polyclonal

纯化方式:

Peptide Affinity Purified

偶联:

FITC

产品浓度:

1 mg/ml

保存温度:

Conjugated antibodies should be stored according to the product label

运输温度:

Blue Ice or 4ºC

存储溶液:

PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated

产地:

加拿大

功能与背景:

The Tumor Necrosis Factor Receptor (TNFR) also known as Cluster of differentiation (CD120) is a protein that belongs to the (TNF)/ (TNFR) superfamily. TNF interacts with two distinct receptors TNFR1 and TNFR2. These receptors share no homology on their cytoplasmic sequences(1,3).TNFR1 also known as p55/p60 is a high affinity receptor for TNF-α. The TNFR1 has an extracellular domain with variable numbers of cysteine-rich repeats. The functional properties of TNFR1 are targets in new therapies for osteoporosis, chronic inflammatory and autoimmune diseases (1, 2). The TNF-α/TNFR1 receptor complex is responsible for the recruitment and the subsequent activation of the caspase (aspartate-specific cysteine proteases) that regulate apoptosis.