UVRAG Antibody: FITC-多抗-深圳欣博盛生物科技有限公司

首页产品中心多抗

UVRAG Antibody: FITC

品牌：Stressmarq

官网链接

说明书

折扣/货期

货号：SPC-606D-FITC

规格：100 µg

目录价：￥4825.8

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

UVRAG Antibody: FITC

别名:

DHTX Antibody, p63 Antibody, UV radiation resistance associated Antibody, UVRAG_HUMAN Antibody

产品描述:

Rabbit Anti-Human UVRAG Polyclonal

反应种属:

Human | Mouse | Rat

宿主来源:

Rabbit

实验应用:

WB | ICC/IF

靶标/特异性:

Predicted molecular weight at ~78.1kDa. Observed molecular weights in the 75-90kDa range.

推荐稀释度:

WB (1:1000); ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

免疫原:

Synthetic peptide from the mid-protein of human UVRAG

免疫原种属:

Human

克隆性:

Polyclonal

纯化方式:

Peptide Affinity Purified

偶联:

FITC

产品浓度:

1 mg/ml

保存温度:

Conjugated antibodies should be stored according to the product label

运输温度:

Blue Ice or 4ºC

存储溶液:

PBS, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated

产地:

加拿大

功能与背景:

UVRAG (UV radiation resistance-associated gene) is associated with the Beclin-1/PI3KC3 complex and promotes PI3KC3 enzymatic activity and autophagy, while suppressing proliferation (1). Beclin-1 binding to UVRAG promotes both autophagosome maturation and endocytic trafficking (2). UVRAG is also a potential tumor suppressor protein with frameshift mutations observed in colon and gastric carcinomas (3-4). It is highly expressed in the brain, lung, kidney and liver.

Accession #:

NP_003360.2