官网链接
折扣/货期| 货号：CDX-P0163-M025 | 规格：25 mg | 目录价：￥1316 |
| 货号：CDX-P0163-M100 | 规格：100 mg | 目录价：￥4382 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Valinomycin
别名:
Potassium ionophore I; Cyclo(L-Val-D-HyIva-D-Val-L-Lac-)3: HyIva = alpha-Hydroxyisovaleric acid, Lac = Lactic acid; NSC 122023
产品描述:
Valinomycin is a cyclododecadepsipeptide antibiotic originially isolated from Streptomyces strains and displays antibacterial efficacy. Valinomycin a neutral ionophore that selectively transfers alkali metal ions via biological and synthetic lipid membranes. Valinomycin is widely used as a selective potassium (K+)-selective ionophore (over Na+) and is an important research tool for membrane and membrane vesicles studies. As ionophore valinomycin has found application as a biosensor to detect potassium (K+) efflux. Valinomycin induces apoptosis in several cell types, including CHO cells, by stimulating potassium efflux and leading to phosphatidylserine membrane translocation, caspase-3 activation, inducing mitochondrial damage and oxidative stress. Valinomycin shows antitumor, antifungal, antiviral, insecticidal and antibacterial effects. Valinomycin as a mitophagy activator also plays a positive role in the treatment of Parkinsons disease and Alzheimers disease. It was recently reported to have antiviral activity against several coronaviruses (FIPV, MERS-CoV, SARS-CoV, HCoV-OC43 or SARS-CoV2).
宿主来源:
Microbial
保存温度:
-20°C
运输温度:
Ambient
预期分子量:
1111.32
产品形式:
solid
产地:
瑞士
纯度:
>95% (HPLC)
CAS号:
2001-95-8
分子式:
C54H90N6O18
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