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折扣/货期| 货号：PM-4937-0.02 mg | 规格：0.02 mg | 目录价：￥1345.5 |
| 货号：PM-4937-0.1 mg | 规格：0.1 mg | 目录价：￥6084 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
XBP-1 Antibody [9B7E5]
别名:
XBP-1 Antibody [9B7E5] : XBP2, TREB5, XBP-1
反应种属:
Human,Mouse,Rat
宿主来源:
Mouse
实验应用:
ELISA,WB,ICC,IF
同种型:
IgG1,k
克隆性:
Monoclonal
克隆号:
9B7E5
纯化方式:
XBP-1 Monoclonal Antibody is immunoaffinity chromotography purified IgG.
偶联:
Unconjugated
产品浓度:
1 mg/mL
保存温度:
XBP-1 monoclonal antibody can be stored at -20˚C, stable for one year.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
XBP-1 Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.
产地:
美国
生产商:
Prosci
功能与背景:
XBP-1 Monoclonal Antibody: X box binding protein 1 (XBP-1) is a key protein in the mammalian unfolded protein response (UPR) that protects the cell against the stress of malfolded proteins in the endoplasmic reticulum (ER). Upon sensing unfolded proteins, an ER transmembrane endonuclease and kinase termed IRE1p is activated and excises an intron from XBP-1 mRNA. The spliced XBP-1 mRNA results in a 371 amino acid protein (XBP-1s) which is then translocated to the nucleus where it binds to the regulatory elements of downstream genes. Together with other UPR transcription factors such as ATF6, XBP-1 stimulates the production of ER stress proteins including the ER resident protein chaperones glucose regulated protein (GRP) 78 and GRP94.
Accession #:
BAB82982
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