XBP-1 Antibody [3H1G4]

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：PM-4935-0.02 mg	规格：0.02 mg	目录价：￥1345.5
货号：PM-4935-0.1 mg	规格：0.1 mg	目录价：￥6084

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

XBP-1 Antibody [3H1G4]

别名:

XBP-1 Antibody [3H1G4] : XBP2, TREB5, XBP-1

反应种属:

Human,Mouse,Rat

宿主来源:

Mouse

实验应用:

ELISA,WB,ICC,IF

同种型:

IgG1

克隆性:

Monoclonal

克隆号:

3H1G4

纯化方式:

XBP-1 Monoclonal Antibody is Protein A purified.

偶联:

Unconjugated

产品浓度:

1 mg/mL

保存温度:

XBP-1 monoclonal antibody can be stored at -20˚C, stable for one year.

运输温度:

Blue Ice

产品形式:

Liquid

存储溶液:

XBP-1 Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.

产地:

美国

生产商:

Prosci

功能与背景:

XBP-1 Monoclonal Antibody: X box binding protein 1 (XBP-1) is a key protein in the mammalian unfolded protein response (UPR) that protects the cell against the stress of malfolded proteins in the endoplasmic reticulum (ER). Upon sensing unfolded proteins, an ER transmembrane endonuclease and kinase termed IRE1p is activated and excises an intron from XBP-1 mRNA. The spliced XBP-1 mRNA results in a 371 amino acid protein (XBP-1s) which is then translocated to the nucleus where it binds to the regulatory elements of downstream genes. Together with other UPR transcription factors such as ATF6, XBP-1 stimulates the production of ER stress proteins including the ER resident protein chaperones glucose regulated protein (GRP) 78 and GRP94.

Accession #:

BAB82982

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