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折扣/货期| 货号：SPC-800D-PCP | 规格：100 µg | 目录价：￥4914 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Alpha Synuclein Antibody: PerCP
别名:
Alpha Synuclein Antibody, Non-A4 component of amyloid precursor Antibody, MGC105443 Antibody, OTTHUMP00000218552 Antibody, MGC110988 Antibody, OTTHUMP00000218553 Antibody, Synuclein alpha 140 Antibody, alphaSYN Antibody, Parkinson disease familial 1 Antibody, OTTHUMP00000218554 Antibody, Parkinson disease (autosomal dominant, Lewy body) 4 Antibody, Synuclein, alpha (non A4 component of amyloid precursor) Antibody, OTTHUMP00000218549 Antibody, Non A4 component of amyloid precursor Antibody, MGC127560 Antibody, SYN Antibody, SNCA Antibody, MGC64356 Antibody, Non A4 component of amyloid Antibody, PARK4 Antibody, Alpha synuclein Antibody, PARK 1 Antibody, Snca synuclein, Synuclein alpha Antibody, Non-A4 component of amyloid, precursor of Antibody, OTTHUMP00000218551 Antibody, PARK 4 Antibody, PARK1 Antibody, Alpha-synuclein, isoform NACP140 Antibody, Non-A-beta component of alzheimers disease amyloid, Non-A beta component of AD amyloid Antibody, NACP Antibody, SYUA_HUMAN Antibody, Alpha-synuclein Antibody, Non A beta component of AD amyloid Antibody
产品描述:
Rabbit Anti-Human Alpha Synuclein Polyclonal
反应种属:
Human | Mouse | Rat
宿主来源:
Rabbit
实验应用:
WB | ELISA | IHC
靶标/特异性:
Detects ~14.46kda.
推荐稀释度:
WB (1:1000); optimal dilutions for assays should be determined by the user.
免疫原:
Recombinant Human alpha Synuclein Fibril
免疫原种属:
Human
克隆性:
Polyclonal
纯化方式:
Protein A Purified
偶联:
PerCP
产品浓度:
1 mg/ml
保存温度:
Conjugated antibodies should be stored according to the product label
运输温度:
Blue Ice or 4ºC
存储溶液:
PBS pH 7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
产地:
加拿大
功能与背景:
Alpha-Synuclein (SNCA) is expressed predominantly in the brain, where it is concentrated in presynaptic nerve terminals (1). Alpha-synuclein is highly expressed in the mitochondria of the olfactory bulb, hippocampus, striatum and thalamus (2). Functionally, it has been shown to significantly interact with tubulin (3), and may serve as a potential microtubule-associated protein. It has also been found to be essential for normal development of the cognitive functions; inactivation may lead to impaired spatial learning and working memory (4).
SNCA fibrillar aggregates represent the major non A-beta component of Alzheimers disease amyloid plaque, and a major component of Lewy body inclusions, and Parkinson's disease. Parkinson's disease (PD) is a common neurodegenerative disorder characterized by the progressive accumulation in selected neurons of protein inclusions containing alpha-synuclein and ubiquitin (5, 6).
Accession #:
NP_000336.1
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