| 货号:SYN-1215-M001 | 规格:1 mg | 目录价:¥1358 |
| 货号:SYN-1215-M005 | 规格:5 mg | 目录价:¥2870 |
| 货号:SYN-1215-M010 | 规格:10 mg | 目录价:¥4844 |
| 货号:SYN-1215-M050 | 规格:50 mg | 目录价:¥12852 |
| 货号:SYN-1215-M100 | 规格:100 mg | 目录价:¥询价 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
GW806742X
别名:
AC1NS7PT; AGN-PC-0LQ49Y
产品描述:
Potent protein kinase VEGFR2 inhibitor (2nm range). Binds to the pseudokinase domain of MLKL and blocks cell death by necroptosis, as well. With regards to its role in necroptosis, it is an ATP-mimetic that was shown to bind recombinant mouse MLKL pseudokinase domain, which showed inhibited TSQ-induced death of mouse dermal fibroblasts by delaying MLKL translocation to the membrane. Appears therefore to be a valuable reagent to inhibit necroptosis. It also provides an important proof-of-principle that targeting catalytically-dead pseudoenzymes represents a feasible, emerging therapeutic avenue.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
573.6
产品形式:
solid
产地:
瑞士
纯度:
>95%
CAS号:
N/A
分子式:
C25H22F3N7O4S
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