深圳欣博盛生物科技有限公司 a1

CD4 Fragment Recombinant Protein
品牌:ProSci LLC
货号:95-105 规格:0.05 mg 目录价:¥4226.625
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
CD4 Fragment Recombinant Protein
别名:
CD4 Antibody : CD4mut
实验应用:
ELISA,WB
表达系统:
E. coli
保存温度:
Store in working aliquots at -70˚C. Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
运输温度:
Dry Ice
产品形式:
Liquid
存储溶液:
100mM sodium phosphate, 500mM NaCl, 25 mM imidazole, 10% gycerol
产地:
美国
生产商:
Prosci
功能与背景:
CD4 is a member of the immunoglobulin superfamily and is implicated as associative recognition element in MHC (Major Histocompatibility Complex) class II-restricted immune response (1). On T-lymphocytes, it defines the helper/inducer subset. The mature 55 kd CD4 protein consists of a 372 amino acid extracellular segment composed of four tandem immunoglobulin-like VJ regions. The CD4 molecule is a major receptor for human immunodeficiency virus (HIV), binding directly to the envelope glycoprotein gp120 on HIV, with the co-receptors being CCR5 or CXCR4. It has been shown that the V-like domains are critical for binding with HIV envelope gp120 (2). This soluble CD4 fragment (sCD4) will work in HIV neutralization assays at levels comparable to previously published results. The minor upper band seen in the Coomassie blue-stained gel is likely to be due to the presence of uncleaved signal sequence.
纯度:
~90%
Accession #:
NP_000607
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