XBP1 Recombinant Protein-其他重组蛋白-深圳欣博盛生物科技有限公司

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XBP1 Recombinant Protein

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：95-109

规格：0.05 mg

目录价：￥4226.625

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

XBP1 Recombinant Protein

别名:

XBP-1 Antibody : XBP2, TREB5, XBP-1

实验应用:

ELISA,WB

表达系统:

E. coli

保存温度:

Store in working aliquots at -70˚C. Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

运输温度:

Dry Ice

产品形式:

Liquid

存储溶液:

1X PBS containing 0.1% SDS

产地:

美国

生产商:

Prosci

功能与背景:

X box binding protein 1 (XBP-1) is a key protein in the mammalian unfolded protein response (UPR) that protects the cell against the stress of malfolded proteins in the endoplasmic reticulum (ER) (1). Upon sensing unfolded proteins, an ER transmembrane endonuclease and kinase termed IRE1p is activated and excises an intron from XBP-1 mRNA. The spliced XBP-1 mRNA results in a 371 amino acid protein (XBP-1s) which is then translocated to the nucleus where it binds to the regulatory elements of downstream genes. Together with other UPR transcription factors such as ATF6, XBP-1 stimulates the production of ER stress proteins including the ER resident protein chaperones glucose regulated protein (GRP) 78 and GRP94 (3,4).

纯度:

~95%

Accession #:

BAB82982

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