| 货号:CDX-E0318-M050 | 规格:50 mg | 目录价:¥1050 |
| 货号:CDX-E0318-M250 | 规格:250 mg | 目录价:¥3416 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Elobixibat hydrate
别名:
A3309; Goofice; Glycine, (2R)-N-[2-[[3,3-dibutyl-2,3,4,5-tetrahydro-7-(methylthio)-1,1-dioxido-5-phenyl-1,5-benzothiazepin-8-yl]oxy]acetyl]-2-phenylglycyl-, hydrate (1:1)
产品描述:
Elobixibat is a selective inhibitor of the ileal bile acid transporter (IBAT, also known as ASBT/SLC10A2), used primarily in research on cholesterol metabolism, bile acid regulation, and gastrointestinal motility disorders. By blocking bile acid reabsorption in the terminal ileum, elobixibat increases bile acid flow into the colon, which stimulates fluid secretion and accelerates colonic transit. Elobixibat lowers LDL cholesterol, increases serum GLP-1, promotes colonic motility and has the potential to treat metabolic syndrome. It has been used in studies on chronic idiopathic constipation (CIC), nonalcoholic fatty liver disease (NAFLD) and hyperlipidemia. Elobixibat is a valuable tool for studying enterohepatic circulation, FXR signaling and gut-liver axis interactions.
宿主来源:
Synthetic
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
713.92
产品形式:
solid
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
1633824-78-8
分子式:
C36H45N3O7S2 . H2O
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