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折扣/货期| 货号：SIH-238-5MG | 规格：5 mg | 目录价：￥5774.4 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Epothilone B
别名:
(1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12,16-pentamethyl-3-[(1E)-1-(2-methyl-1,3-thiazol-4-yl)-1-propen-2-yl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione, Patupilone
产品描述:
Microtubule stabilizer
保存温度:
-20ºC
运输温度:
Shipped Ambient
预期分子量:
507.68
产品形式:
White Solid
产地:
加拿大
功能与背景:
Epothilone are a new class of cancer drugs. They prevent cancer cells from dividing by interfering with tubulin (1). Epithilone B possess the same biological effects as paclitaxel in both invitro and cultured cells, because they share the same binding site (2). Epothilone has also been shown to induce tubulin polymerization into microtubules without the presence of GTP. And it also causes cell cycle arrest at the G2-M transition phase, leading to eventual cell apoptosis (3). It is considered Neurotrophic - it has been found to promote axon regeneration.
纯度:
>98%
来源:
Synthetic
CAS号:
152044-54-7
分子式:
C27H41NO6S
溶解度:
Soluble to 10 mM in DMSO
PubChem CID:
448013
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