Epoxomicin-其他小分子化合物-深圳欣博盛生物科技有限公司

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Epoxomicin

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-CN2-0422-C050	规格：50 ug	目录价：￥840
货号：AG-CN2-0422-C100	规格：100 ug	目录价：￥1440
货号：AG-CN2-0422-C250	规格：250 ug	目录价：￥2880
货号：AG-CN2-0422-C500	规格：500 ug	目录价：￥4320

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Epoxomicin

别名:

Antibiotic BU 4061T

产品描述:

Antibiotic [1]. Potent anticancer compound [1, 7]. Cell permeable, potent, selective and irreversible 20S proteasome inhibitor. Predominantly inhibits the chymotrypsin-like (CTRL) activity of the proteasome. Exhibits lower level inhibition of proteasome trypsin-like and caspase-like activitives (100 and 1,000-fold slower rates respectively) [2, 3]. Anti-inflammatory [4]. Antimicrobial and antimalarial [8]. Anti-parasitic [9]. Stimulates bone formation by inhibiting osteoblast proteasome activity [5]. Induces Parkinson's-like symptoms in rats [6]. The ubiquitin-proteasome system (UPS) and autophagy serve as two complementary, reciprocally regulated protein degradation systems. Blockade of UPS by Epoxomicin activates autophagy. Blocks the Thymoproteasome beta5t subunit activity.

宿主来源:

Synthetic.

保存温度:

+4°C

运输温度:

Ambient

预期分子量:

554.7

产品形式:

solid

产地:

瑞士