官网链接
折扣/货期| 货号：AG-CN2-0422-C050 | 规格：50 ug | 目录价：￥840 |
| 货号：AG-CN2-0422-C100 | 规格：100 ug | 目录价：￥1440 |
| 货号：AG-CN2-0422-C250 | 规格：250 ug | 目录价：￥2880 |
| 货号：AG-CN2-0422-C500 | 规格：500 ug | 目录价：￥4320 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Epoxomicin
别名:
Antibiotic BU 4061T
产品描述:
Antibiotic [1]. Potent anticancer compound [1, 7]. Cell permeable, potent, selective and irreversible 20S proteasome inhibitor. Predominantly inhibits the chymotrypsin-like (CTRL) activity of the proteasome. Exhibits lower level inhibition of proteasome trypsin-like and caspase-like activitives (100 and 1,000-fold slower rates respectively) [2, 3]. Anti-inflammatory [4]. Antimicrobial and antimalarial [8]. Anti-parasitic [9]. Stimulates bone formation by inhibiting osteoblast proteasome activity [5]. Induces Parkinson's-like symptoms in rats [6]. The ubiquitin-proteasome system (UPS) and autophagy serve as two complementary, reciprocally regulated protein degradation systems. Blockade of UPS by Epoxomicin activates autophagy. Blocks the Thymoproteasome beta5t subunit activity.
宿主来源:
Synthetic.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
554.7
产品形式:
solid
产地:
瑞士
纯度:
>97% (HPLC)
CAS号:
134381-21-8
分子式:
C28H50N4O7
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