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折扣/货期| 货号：CDX-E0574-M001 | 规格：1 ml | 目录价：￥2772 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Everolimus Solution
别名:
42-O-(2-Hydroxyethyl)rapamycin; NVP-RAD001; RAD001; SDZRAD; Zortress; Afinitor; Certican; Votubia
产品描述:
Macrolide antibiotic, inhibiting bacterial protein synthesis. Potent immunosuppressant. Binds with high affinity to the FK506 binding protein-12 (FKBP-12) to generate an immunosuppressive complex that inhibits the activation of the mammalian target of rapamycin (mTOR). More selective for the mTORC1 protein complex, with little impact on the mTORC2 complex, compared to Rapamycin. Anticancer agent. Inhibition of mTOR reduces the activity of effectors downstream, which leads to a blockage in the progression of cells from G1 into S phase, and subsequently inducing cell growth arrest, apoptosis and autophagy, resulting in reduction of cell proliferation, angiogenesis and glucose uptake. Inhibits tumor proliferation in vitro and in vivo. This compound can be used as a reference material.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
958.22
产品形式:
liquid
产地:
瑞士
纯度:
>99% (HPLC)
CAS号:
159351-69-6
分子式:
C53H83NO14
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